"I am surprised by how not-adopted the video reply has been. What keeps other people from doing it, I think, is that they think a video comes across as 'I'm cool, look at how many e-mails I get.' That perception doesn't scare me, because I know who I am."

"I always say that the real success of Wine Library wasn't due to the videos I posted, but to the hours I spent talking to people online afterward, making connections and building relationships."

"I find it fascinating that a lot of business books that do well are from people who've never made any money in business."

"People who build family businesses are not classically trained. They have to deal with an enormous amount of politics. You think corporate politics are tough? Go work for your dad or your mom."

"Science reckons many prophets, but there is not even a promise of a Messiah."

"Ignorance more frequently begets confidence than does knowledge: it is those who know little, and not those who know much, who so positively assert that this or that problem will never be solved by science."

"The media thinks that you have to make science sexy and concentrate on themes such as rivalry and the human issues."

"Everything in the universe has a purpose. Indeed, the invisible intelligence that flows through everything in a purposeful fashion is also flowing through you."